Released on = September 12, 2006, 11:16 am

Press Release Author = Debra Thai

Industry = Biotech

Press Release Summary = Apoptosis, a programmed, cell-autonomous death process,
plays important roles in a variety of physiological and pathological events (1).

Press Release Body = These range from normal fetal development to diseases, such as
cancer (2), organ failure and neurodegenerative diseases. During apoptosis, caspases
execute the disassembly of cellular components by proteolytic cleavage of a variety
of substrates, such as poly-(ADP ribose) polymerase (3), DNA-dependent protein
kinase (DNA-PK), topoisomerases, and protein kinase C delta (4). At least ten
caspases have been discovered. Some of these caspases identify and cleave a specific
peptide substrate, while others recognize the same peptide substrate (4).

AnaSpec's line of EnzoLyteT Caspase Assay Kits are optimized for high-throughput
screening. HTS-optimized features include: one-step homogeneous assays, a
convenient mix-and-read format, and highly sensitive fluorimetric components.

EnzoLyteT Homogeneous Caspase-3/7 Assay Kits
- For detecting caspase 3/7 activity in cells and/or for screening caspase 3/7
inducers or inhibitors
- Measures activity directly in 96- or 384-well microplate, bifunctional lysis
buffer lyses cells as well as provides optimal buffer condition for caspase 3/7
activity

EnzoLyteT Homogeneous AFC Caspase-3/7 Assay Kit
· 500 assays in 96-well format
· Ex/Em(nm)

Web Site = http://http://www.anaspec.com/products/promotions.asp?col

Contact Details = 2149 O\'Toole Ave.
San Jose, CA 95131
Tel: 800-452-5530
Fax: 408-452-5055
info@anaspec.com
marketing@anaspec.com
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